Scientists have created a more efficient and controlled way to produce lab-grown inner ear hair cells than current methods ...

A new study led by Children's Hospital Los Angeles has found a novel mechanism behind neuroblastoma progression: the shape and structure of the extracellular matrix.

This type of framework has been suggested recently for modeling cell-signaling pathways (11). The question is thus begged as to whether this bacterial chemotaxis signaling pathway is essentially ...

The monolayer of endothelial cells lining the vessel wall forms a semipermeable barrier (in all tissue except the relatively impermeable blood–brain and inner retinal barriers) that regulates ...

Most cells in the body send out little messengers called extracellular vesicles that carry proteins, lipids, and other bioactive molecules to other cells, playing an important role in ...

In this review, we discuss the role of major Ca 2+ signaling pathways found in airway epithelial cells and their contributions to airway inflammation, mucociliary clearance, and surfactant production.

Brain cells, or neurons, have multiple means of communication, and their chatter may be influenced by the cells around them, research suggests.

The utilization of intracellular metabolic resources and cell survival, proliferation, and differentiation are all related to the integration of metabolic and signaling pathways.

Chimeric antigen receptor (CAR) is a single-pass transmembrane receptor designed to specifically target and eliminate cancers. While CARs prove highly efficacious against B cell malignancies, the ...

We created workflows with tutorials to facilitate the analysis of cell–cell interactions and affected downstream intracellular signaling processes. OmniPath provides a single access point to knowledge ...

2 O’Neal Comprehensive Cancer Center, School of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States The Notch signaling pathway plays an essential role in a wide variety of ...