In the process of low-temperature plasma discharge in atmospheric-pressure humid air, which involves numerous species and a myriad of reactions, the system exhibits a highly nonlinear behavior, making ...

Rationale: Mutations in the LMNA gene, encoding LMNA (lamin A/C), are responsible for laminopathies. Dilated cardiomyopathy (DCM) is a major cause of mortality and morbidity in laminopathies.

Kyoto encyclopedia of genes and genomes (KEGG) enrichment analysis revealed the top 20 enriched metabolic pathways, including phenylpropanoid biosynthesis (ko00940), MAPK signaling pathway (ko4016), ...

Figure 4 LBP treatment increases the Nrf2 accumulation in nucleus by activating Keap1- Nrf2∕ARE signaling pathway. (A) Immunohistochemical study of Nrf2 positive cells in kidney tissue after different ...

Summary A study led by Weill Cornell Medicine reveals that the APOE3-R136S mutation delays Alzheimer’s disease by inhibiting the cGAS-STING immune pathway. This mutation suppresses inflammation in ...

This rare mutation is found in the APOE gene encoding a cholesterol transport protein (apolipoprotein E), and was first discovered by a laboratory in Christchurch, New Zealand. In 2019, scientists ...

A rare gene mutation that delays Alzheimer's disease does so by damping inflammatory signaling in brain-resident immune cells, according to a preclinical study led by investigators at Weill ...

Oxidative stress plays a vital role in the development of cerebral ischemic/reperfusion (I/R). Targeting oxidative stress is proposed to be an effective strategy to treat cerebral I/R injury. Gentiana ...