No one can live without a heart pumping blood to the rest of the body. New research from the University of Missouri School of ...

Learn more about the research of Mayo Clinic's Gene Editing and Cellular Engineering Laboratory led by David (Chun-Wei) D.

FAST kinase domain-containing protein 5 (FASTKD5) is a mitochondrial protein that is needed for processing mRNA in the primary mitochondrial transcript. Several mutations have been found in other ...

Researchers at Karolinska Institutet have discovered a previously unknown molecule that may explain why people with type 2 ...

PMR-116 shows promise in treating MYC-driven cancers, offering hope for patients with aggressive tumors in upcoming human trials.

An orthogonal study identified MYC amplification as an unfavorable prognostic factor using targeted next-generation sequencing. The purpose of this study was to validate the independent prognostic ...

The MYC protein is a well-established driver in up to 70% of human cancers, but has long been considered “undruggable” due to the absence of suitable binding pockets for high-affinity small ...

Scientists suggest understanding ecDNA’s role in pancreatic cancer could potentially guide future strategies for making tumors more vulnerable to treatment.

UCSF scientists discover how cancer cells hijack the protein factory of the cell to churn out MYC protein, the driver of 70% of all cancers.

c-MYC controls global gene expression and regulates cell proliferation, cell differentiation, cell cycle, metabolism and apoptosis. According to some estimates, MYC is dysregulated in ≈70% of human ...

Researchers from the Eisenman Lab create and study a new mouse model of MYC-associated cancer, revealing surprising nuance in the effects of the oncogenic T58A MYC mutation that differentiates it from ...