In this protocol, which is known as the multiple-dose methotrexate protocol, methotrexate is given at a dose of 1 mg/kg intramuscularly on days 1, 3, 5 and 7.

Objective This study assessed the early effects of ozoralizumab (OZR) 30 mg in patients with rheumatoid arthritis (RA) with inadequate response to methotrexate (MTX-IR), drawing on OHZORA trial data ...