The role of oxidative stress, as well as inflammation in the pathogenesis of methotrexate (MTX)-induced oral mucositis, is a known fact. The anti-inflammatory, antitumor, antimicrobial, and ...

Methotrexate's prospects got a boost 2 years ago when researchers reported that the drug produced an average 15.2-point reduction in pain scores after 6 months in hand OA patients, compared with 7 ...

Mucositis was induced in hamsters by intraperitoneal injection of 5-fluorouracil on days 0 and 2, and the left cheek pouch was irritated by superficial scratching on days 3 and 4. In group I, oral ...

Prednisone is recommended as the first-line treatment for pulmonary sarcoidosis, but this steroid causes a number of unwanted side effects.

Oropharyngeal mucositis may be a distressing side effect of chemotherapy and irradiation. This comprehensive review offers recommendations to reduce symptoms and improve functioning.

One of the key interventions for prevention and reduction of severity of oral mucositis is oral cryotherapy in conjunction with basic oral care.

Study: ENT-1-Targeted Polymersomes to Enhance the Efficacy of Methotrexate in Choriocarcinoma Treatment. Image Credit: Shutterstock AI Generator / Shutterstock.com In a recent study published in ...

No previous study has investigated whether glucarpidase improves important clinical outcomes in patients with methotrexate-associated acute kidney injury (AKI).

One week after high-dose methotrexate treatment, plasma citrulline levels dropped to median levels of 14.5 μM for patients treated according to a particular protocol and to 16.9 μM according to ...

Methotrexate injection is used to treat certain autoimmune conditions and some types of cancer. Learn about mild and serious side effects and how to manage them.

Raising awareness about mucositis and its impact on cancer patients is vital in providing comprehensive care during cancer treatment.