For decades, the dream of fixing harmful mutations in mitochondrial DNA felt out of reach. Scientists have long known these ...

Mitochondria are cell organelles surrounded by a double membrane. In addition to numerous essential functions in the ...

Home > Press release: Immune system response to viral ...

Building on serum metabolites analysis in rosacea, researchers have identified linoleic acid (LNA) as a key therapeutic ...

Under normal conditions, when mitochondria maintain a delicate balance of ions inside and outside their double membrane—in other words, their membrane potential—PINK1 is whisked across the outer layer ...

The mitochondria The mitochondria are the key organelle responsible for aerobic respiration and generates most of the cell's ATP. The mitochondria are membrane-bound organelles found in eukaryotic ...

Scholkmann, F. (2016) Long Range Physical Cell-to-Cell Signalling via Mitochondria Inside Membrane Nanotubes A Hypothesis. Theoretical Biology and Medical Modelling, 13, Article No. 16.

We found that cardiolipin (CL) specifically buffers the inner mitochondrial membrane against curvature loss, an effect that is independent of ATP synthase dimerization. To explain this interaction, we ...

This process of mitochondrial pore-regulated cell death has been observed in a range of conditions, including heart muscle damage after heart attacks and neurodegenerative diseases.

Results provide new insights for apoptosis research, and could lead to opportunities to explore Bax and its relatives as interesting targets in cancer therapy.

The modern mitochondria consists of a double membrane system with the inner and outer mitochondrial membranes separated by an intermembrane space. The inner mitochondrial membrane is a thick, gel-like ...

A new study reveals that the protein MTCH2, which is essential in a variety of cellular processes, is responsible for shuttling various other proteins into the membrane of mitochondria. The ...