Primary mitochondrial disorders are a group of greater than 200 single gene defects arising from two genomes (nuclear and mitochondrial) leading to mitochondrial dysfunction, and are associated with ...

For decades, the dream of fixing harmful mutations in mitochondrial DNA felt out of reach. Scientists have long known these ...

In August 2023, this American child, whom we will call J., was doing well. He was playing sports and leading a normal life.

Mitochondria are cell organelles surrounded by a double membrane. In addition to numerous essential functions in the ...

The value of a recent biochemical discovery can be seen in the case of an 8-year-old boy. In August 2023 he was able to play typical sports, but by November he needed a wheelchair because of a rare ...