Discover how Adipotide, a promising peptide, could revolutionise our understanding of adipose tissue dynamics and metabolic regulation, paving the way for innovative therapies.

An international team led by researchers at The Hospital for Sick Children (SickKids), Princess Margaret Cancer Centre, ...

A research team led by Professor Koji Eto revealed that disruptions of the KCNN4 potassium channel impair mitochondrial ...

Breast cancer, particularly triple-negative breast cancer (TNBC), remains a leading cause of cancer-related mortality due to its aggressive nature and ...

Dysregulation of mitochondrial dynamics has been linked to impaired development and cancer progression, including breast cancer metastasis.

Mitochondrial dynamics are pivotal in breast cancer metastasis, influencing metabolic flexibility, stemness, and therapy resistance. Targeting fission, fusion, and mitophagy offers a ...

However, limited studies are available that report any epigenetic changes in the offspring following a stroke in mothers. In the present study we investigate the effect of stroke in pregnancy as a ...

Our cells harbor a DNA detector termed cGAS to inform the immune system of viral and bacterial infections, cell death, as well as transformation during cancer. Researchers led by Ikerbasque Research ...

The central goal of research in the Mears Lab is to investigate proteins that regulate mitochondrial dynamics. Mitochondrial dynamics has recently come to the forefront as a therapeutic target in ...

Mitochondrial carrier homolog 2 (MTCH2) is a regulator of apoptosis, mitochondrial dynamics, and metabolism. Loss of MTCH2 results in mitochondrial fragmentation, an increase in whole-body energy ...

However, the high dynamics and phenotypic heterogeneity of mitochondria require high-resolution characterization within individual living cells. Therefore, we introduce a fluorescence analysis method, ...