In this study, researcher developed a new imaging approach that combines two powerful techniques to solve this problem. First ...

Discover how Adipotide, a promising peptide, could revolutionise our understanding of adipose tissue dynamics and metabolic regulation, paving the way for innovative therapies.

A research team led by Professor Koji Eto revealed that disruptions of the KCNN4 potassium channel impair mitochondrial ...

Dysregulation of mitochondrial dynamics has been linked to impaired development and cancer progression, including breast cancer metastasis.

Mitochondrial dynamics are pivotal in breast cancer metastasis, influencing metabolic flexibility, stemness, and therapy resistance. Targeting fission, fusion, and mitophagy offers a ...

Di-(2-ethylhexyl) phthalate (DEHP), a ubiquitous environmental pollutant, significantly impairs the male reproductive function. Astaxanthin (ASX), a natural carotenoid with potent antioxidant ...

In contrast to their role in cell types with higher energy demands, mitochondria in endothelial cells primarily function in signaling cellular responses to environmental cues. This article provides an ...

It is also recognized that mitochondrial abnormalities not only act by altering metabolism but, through effects on mitochondrial dynamics, can regulate numerous cellular processes including ...

While this further highlights the importance of peroxisome/mitochondria dynamics in the brain, the exact pathophysiological mechanisms remain unclear, and the relative contribution of the peroxisomal ...

Loss of UBR4 causes mitochondrial dysfunction, excessive reactive oxygen species, cell cycle arrest, and senescence while avoiding apoptosis. Interestingly, UBR4 inactivation impairs tumor growth by ...

Apoptosis has been causally linked to the pathogenesis of myocardial infarction and heart failure in rodent models. This death process is mediated by two central pathways, an extrinsic pathway ...