CCHD pathogenesis and progression are associated with mitochondrial dysfunction through changes in metabolism, fission, and fusion.

Mitochondria dysfunction promotes apoptosis, participates in regulating the signaling pathways of mitochondrial antioxidants and mitochondrial growth, and has become a therapeutic target for studying ...

It is also recognized that mitochondrial abnormalities not only act by altering metabolism but, through effects on mitochondrial dynamics, can regulate numerous cellular processes including ...