Authors also states that Ccr4-deficient Tregs had, as expected, impaired migration to the atherosclerotic aorta. Adoptive cell transfer of Ccr4-/- Tregs to Apoe-/- mice mimicked early atherosclerosis ...

Immunohistochemistry (IHC) staining provides precise localization and qualitative analysis for tumor diagnosis, while its application is often constrained by complexity and high costs. Recently, many ...

Rationale: Abdominal aortic aneurysms (AAAs) are a chronic inflammatory vascular disease for which pharmacological treatments are not available. A mouse model of AAA formation involves chronic ...

Animal studies are a foundation for defining mechanisms of atherosclerosis and potential targets of drugs to prevent lesion development or reverse the disease. In the current literature, it is common ...

Increased eosinophil levels in COPD were associated with impaired abdominal aortic dynamics, highlighting a mechanistic link between eosinophilic inflammation and vascular dysfunction.