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tuberculosis, this tag showed up in the outer layer of the cell wall. When the researchers exposed the label to Mycobacterium smegmatis, a related bacterium that does not cause disease and does not ...
We thank Phillip Ipock for experimental support, Dr. Daria Kim for helpful discussions, and Dr. D. Branch Moody for reading and commenting on the manuscript. We also thank Dr. Thomas Dieffenbach of ...
Macrophages infected with Mycobacterium tuberculosis were fixed and imaged at four hours and 72 h postinfection. (Scale bar, 4 μm.) LAM labeling with oxaziridines persists for up to 72 h.
The subject of Aldridge’s research is the bacterium Mycobacterium tuberculosis, the causative agent of tuberculosis. In 2023, TB made 10.8 million people sick and killed around 1.25 million people.
Mycobacterium tuberculosis remains a leading cause of infectious disease morbidity and mortality for which new drug combination therapies are needed. Mycobacterial bioenergetics has emerged as a ...