Janus kinase (JAK) inhibitors are associated with decreased mortality and fewer serious adverse events among adults hospitalized with COVID-19.

Leading companies, such as Incyte Corporation, TWi Biotechnology, Amgen, Pfizer, Arcutis Biotherapeutics, AnaptysBio, and others, are actively advancing promising drug candidates aimed at improving ...

Immune checkpoint inhibitors have changed the future of cancer care. These powerful treatments use the body’s own immune ...

In part 1, experts explores how assessing individual risk factors is crucial in selecting the appropriate JAK inhibitor for patients with myelofibrosis.

Researchers examined the risk for serious infection among patients with atopic dermatitis treated with Janus kinase inhibitors vs Th2 cytokine inhibitors.

Janus kinase inhibitors (JAKis) are an important treatment option for people with chronic inflammatory diseases such as rheumatoid arthritis, psoriasis, Crohn's disease or ulcerative colitis ...

This article explores the advancements of JAK inhibitors in MF, highlighting benefits, limitations, and potential future developments.

This harmful condition is sustained by interferon-gamma-expressing natural killer cells and cytotoxic T cells. Our study found that blocking the JAK pathway using inhibitors can prevent and reverse ...

Janus kinase inhibitors (JAKis) represent a fundamental therapeutic tool for the treatment of patients with immune-mediated inflammatory diseases. Although JAKis are often considered a homogeneous ...

Janus kinase (JAK) inhibitor-associated acne may be overlooked outside of dermatology, experts said.

It occurs when a faulty immune system attacks healthy hair follicles. Alopecia universalis is a severe form of alopecia ...