At some point during the evolution of life on Earth, inorganic matter became organic, nonliving matter became living. How ...

The RSC Nucleic Acids Group invites you to their Forum meeting, which will take place in-person at the RSC's iconic Burlington House in London. This is the NAG’s annual meeting, bringing together the ...

Here we present a microRNA (miRNA) knockdown application, based on the use of Locked Nucleic Acid (LNA™)-modified probes. The use of LNA for the knockdown of miRNA is particularly effective ...

The variety of potentially useful dyes or haptenes available for fluorescent nucleic acid hybridization assays is far greater than what can be obtained from commercial sources 1,2. Since this ...

The Nucleic Acid Structure and Recognition Lab at Mayo Clinic studies DNA flexibility, novel DNA-RNA-based drug therapies and rare cancers.

Education, training and mentorship are vital components of the research activities in the Nucleic Acid Structure and Recognition Lab. Dr. Maher has been a leader in graduate education since 1991, ...

Therapeutic development for central nervous system (CNS) disorders remains hindered by inefficient drug penetration across the blood–brain barrier (BBB) and a lack of spatiotemporal precision ...

Despite the pivotal role of nucleic acids in these networks, their contributions to allostery have largely been overlooked. To address this gap, we developed ComPASS, a large-scale computational ...