Chemists have previously built a wide range of entangled structures, including catenanes, which contain interlocked rings, and molecular knots. These have often been constructed around metal ions ...

Why ‘life is handed’ – why the chiral amino acids that make up proteins and the chiral sugars in nucleic acids are present only in one of the two possible enantiomeric forms – is one of the most ...

DNA is fundamental to the biology of all life on Earth, but how many of us actually know what it is or what it's made of?

DNA stands for deoxyribonucleic acid. Nucleic acids are named for where they're found—inside the nuclei of cells—and for the acidic phosphate groups discovered in solution wherever DNA is present.

Comparing Nucleic Acid Isolation Techniques To obtain high-quality, purified nucleic acids, scientists can use several different methods, including phenol-chloroform extraction, cesium ...

The structure and function of nucleic acids The structure and function of nucleic acids Nucleic acids are essential biomacromolecules that carry or contain genetic information. They can be separated ...

Although nucleic acids modifications have traditionally been associated with small chemical groups, such as methyl (for example, in the case of N6-methyladenosine, m6A), our investigation demonstrates ...

Impact As a nucleic acid, EAA can be easily synthesized with nucleic acid therapeutics, enabling their efficient loading on exosomes without conjugation or modification orthogonal to CD63-binding ...

Our exploration of the spontaneous chemical copying of a range of nucleic acid templates by activated 2′-amino 2′,3′-dideoxyribonucleotide monomers highlights both the advantages and potential ...

Advanced smart nanoparticles enhance the delivery of nucleic acid therapeutics to cancer cells, addressing many of the barriers that have hindered their clinical applications, according to a ...