Periadventitial adipose tissue promotes endothelial dysfunction via oxidative stress in diet ... Irisin improves perivascular adipose tissue dysfunction via regulation of the heme oxygenase-1 ...

The prevalence of obesity has been increasing in the US. In 2017–2018, the prevalence was 42.4%, an increase from 30.5% in 1999-2000. 1 Obesity is linked to numerous health problems, many of ...

Plasminogen activator inhibitor-1 (PAI-1), the physiologic inhibitor of tissue-type plasminogen activator (t-PA), has emerged to an early prominent bridge builder between atherothrombosis and ...

David Manka, PhD, a researcher in the division of cardiovascular diseases, and his team found that this fat -- known as perivascular adipose tissue -- could possibly lead to the formation of fatty ...

By replicating conditions like tissue stiffening and scarring - common in aging, chronic diseases and cancer - the researchers discovered that perivascular cells drive blood vessel leakage and ...

Guzik, TJ, Skiba DS, Touyz RM, Harrison DG. The role of infiltrating immune cells in dysfunctional adipose tissue. Cardiovasc Res. 2017; 113: 1009-1023. Crossref 7.Madonna R, Massaro M, Scoditti E, et ...

This study demonstrates that global or adipose tissue-specific knockout of CIDEC/FSP27 significantly reduces AAA incidence after HFD treatment and Ang Ⅱ infusion, providing novel insights into ...

Previous research showed that obesity heightens the risk of severe COVID-19 regardless of age, sex, ethnicity and comorbidities such as diabetes, high blood pressure, and heart or lung disease ...

Based on perivascular adipose-tissue samples and coronary CT images from more than 400 patients, they developed a "fat-attenuation index" (FAI) that correlates with coronary artery inflammation ...

Psoriasis linked to adipose dysfunction Patients with psoriasis have lower plasma adiponectin, higher plasma leptin levels. Inflammation present in psoriasis may be associated with adipose tissue ...