Obesity is causally linked with the development of cardiovascular disorders. Accumulating evidence indicates that cardiovascular disease is the collateral damage of obesity-driven adipose tissue ...

Background: Thoracic aortic aneurysm (TAA) is a life-threatening disease with high morbidity and mortality rates due to fatal complications such as aortic rupture. However, molecular mechanisms ...

Over the last years, perivascular adipose tissue (PVAT) has emerged as an adipose organ with endocrine and paracrine functions. Pro and anti-inflammatory agents released by PVAT affect vascular health ...

Results reveal that weight loss has significant effects on cellular processes that are known to affect metabolic health and ...

Obesity has reached epidemic proportions worldwide, posing a significant burden on people’s health and on healthcare systems. It is a major risk factor for ...

Chronic kidney disease (CKD) is typically associated with severe fibrosis, the exact pathogenesis of which remains unclear.

Introduction The importance of the endothelium in human health and disease was a major topic of discussion at the Annual Meeting of the American College of Clinical Pharmacy, November 5-8, 2000 ...

Adipose tissue (AT) is no longer viewed as a passive, energy-storing depot, and a growing body of evidence supports the concept that both quantitative and qualitative aspects of AT are critical in ...

This research aimed to investigate the antihypertensive effects of YYLLVR, a peptide derived from hazelnut, to improve endothelial dysfunction in spontaneously hypertensive rats (SHRs). YYLLVR decr ...