Repeated exercise bouts (exercise-training) have been demonstrated to increases GLUT4 concentrations in populations with metabolic syndrome (MetS) and T2D, 15 and these increases are associated with ...

Although adipose tissue quantity (volume) is undoubtedly linked to cardiovascular risk, recent human data indicate that differences in fat tissue quality, which can be examined directly by ...

Liu et al. (70) isolated exosomes from the perivascular adipose tissue (PVAT) and subcutaneous adipose tissue (SCAT) of C57BL/6J mice of wild type. The results revealed that PVAT-exosomes ameliorated ...

In contrast, blocking the action of CLCF1 made exercise ineffective, confirming that this protein is essential for the beneficial effects of exercise. Further analysis showed that CLCF1 enhances ...

Aim: To explore the characteristics of perivascular adipose tissue (PVAT) around atherosclerotic vessels in patients with coronary heart disease(CHD). Methods: PVAT around the proximal ascending aorta ...

Figure 1. Pathways linking local obesity-induced inflammation to systemic insulin resistance. Obesity results in the activation of the inflammatory signaling pathways mediated by JNK and nuclear ...

Enlarged white adipose tissue (WAT) is a feature of obesity and leads to changes in its paracrine and endocrine function. Dysfunction of WAT cells is associated with obesity-associated disorders like ...

This review aims to determine how lactate participates in energy supply and elaborate on how lactate is involved in the fat metabolism and regulation of white adipose and skeletal muscle tissues ...