Boltz-2 is an open-source biomolecular model achieving near-FEP accuracy with 1000x faster predictions for structure and binding affinity. Quiver AI Summary MIT and Recursion have released Boltz-2 ...

The structure of FSP1 was recently solved (20 – 23), revealing a double Rossman-fold oxidoreductase with NAD (P)H, FAD, and substrate-binding domains. Cotranslational modification of FSP1 by the ...

The cryo-EM structure of human myoferlin elucidates the organization of its seven C 2 and accessory domains upon concerted membrane-binding, enabling us to identify the precise motifs involved in ...

A cryo-EM structure of TWIK-2 in complex with pimozide identifies its binding location and mechanism of inhibition. The work provides a structural foundation for development of specific TWIK-2 ...

NEW YORK-- (BUSINESS WIRE)-- VantAI today unveiled Neo-1, the world’s most advanced atomistic foundation model and the first to unify de novo molecular generation with multimodal structure ...

To enhance the sustainability of nuclear energy and protect the environment, the efficient extraction of uranium from various water sources has emerged as an essential strategy for addressing the long ...

These include the C-H and C-N bonds in the imide ring and C-C bonds connecting the imide structure to the benzene ring, leading to the generation of gaseous byproducts like CO and H2 O. Concurrently, ...

Immunomodulatory imide drugs are analogs of the drug thalidomide that possess pleiotropic anti-myeloma actions. These comprise of anti-proliferative, anti-angiogenic, immune-modulatory and, in ...

Polyimides can additionally be thermosetting, where imide oligomers are crosslinked into a network that is three-dimensional. Examples of thermoset polyimides are PETI ® and PMR-15 ® matrix resins for ...