A team has made a major breakthrough in the field of three-dimensional (3D) imaging of large-scale biological tissues. They ...

Myasthenia gravis (MG) results from autoimmune antibodies against the post-synaptic neuromuscular junction with three major ...

Odronextamab (Ordspono) given as a monotherapy demonstrated encouraging efficacy and had a generally manageable safety profile when used for the treatment of patients with diffuse large B-cell ...

As neuronal supporters and immune surveyors, astrocytes and microglia are no mere bystanders to the neuronal mayhem that unfolds in Alzheimer’s disease. At the AD/PD meeting, held March 5-9 in Lisbon, ...

In this study we examine the efficiency of RVdG retrograde spread from starter cell to input neurons at the synaptic level. We designed a new genetically modified rabies virus that labels presynaptic ...

Background: PURE-01 trial enrolled 155 patients who received 3 cycles of pembrolizumab (IO) every 3 weeks before radical cystectomy. We compared tumor-microenvironment immune markers expression in pre ...

03 Sep 2021 That Aβ begets tau pathology is the central premise of the amyloid cascade hypothesis of Alzheimer’s disease. But how exactly does the begetting happen? A paper published August 31 in Cell ...

Abstract Apical intercalated cell cluster: A distinct sensory regulator in the amygdala Highlights • ApITCs receive inputs from thalamic nuclei and association cortical areas • Thalamic inputs to ...

We then analyzed pre‐ and post‐synaptic regions for mitochondrial translation using HPG labeling. As a marker for pre‐synaptic sites, we labeled synaptic vesicles with an antibody against vesicular ...