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Simply 'sprinkling' a fluorescent probe can quickly show active brain synapses
There are few scientific methods more elegantly simple than "just sprinkle it on top." Researchers at Tohoku University and ...
3D imaging system reveals fine architecture of peripheral nervous systems in mouse body
A team has made a major breakthrough in the field of three-dimensional (3D) imaging of large-scale biological tissues. They ...
eLife8d
Assemblies, synapse clustering, and network topology interact with plasticity to explain structure-function relationships of the cortical connectome
This useful study presents a biologically realistic, large-scale cortical model of the rat's non-barrel somatosensory cortex, investigating synaptic plasticity of excitatory connections under varying ...
Nature24d
NMDA receptors amplify calcium influx into dendritic spines ... - Nature
Abstract Long-term potentiation (LTP) of synaptic strength can be induced by synchronous pre- and post-synaptic activation, and a rise in postsynaptic calcium is essential for induction of LTP.