For cell adhesion molecules, a critical unanswered question is whether pre- and post-synaptic partners contribute equally to synaptogenesis, ...

For cell adhesion molecules, a critical unanswered question is whether pre- and post-synaptic partners contribute equally to synaptogenesis, ...

While Zador’s group was successful in joining pre- and post- synaptic barcodes as a proof of concept, their initial experiments resulted in a high frequency of false positives. Further dilution of the ...

While it has often been suggested1–3 that these “synaptic vesicles” contain transmitter molecules discharged into the intercellular gap between pre- and post-synaptic surfaces when ...

The neuron becomes pre and post synaptic at the same time. "Such a controlled neuronal system allows us studying in vitro glial factors individually," says Llobet.

Studying the complex interactions between synaptic nerve endings as well as their development has now become much easier. Thanks to a method developed by scientists of the Karl Landsteiner University ...

Also, for the first time, it now is possible to analyze pre- and postsynaptic effects of wild-type and/or genetically modified synapses in a simple neuronal network. This methodological advance will ...

In response, post-synaptic neurons enter a state of synaptic long-term depression (LTD), which, in turn, instigates an AD-like hyperphosphorylation of tau. Though individual parts of this pathway have ...