The ability to undergo large-scale domain rearrangements is essential for the substrate-binding function of periplasmic binding proteins (PBPs), which are indispensable for nutrient uptake in ...

Credit: Genes & Development (2025). DOI: 10.1101/gad.352498.124 Scientists have discovered a protein that enables bacteria to shut down into dormant spores under extreme conditions.

The global protein expression market was worth at USD 4.24 billion in 2023 and is projected to grow USD 12.27 billion by 2033 from USD 4.68 billion in 2024, growing at a CAGR of 10.45% from 2024 to ...

An unexpected find has enabled important progress to be made in the battle against harmful bacteria. An international team of researchers, led by Professor Peter Fineran from the University of ...

However, they are typically sensitive to proteases and other modes of degradation, and each type of antimicrobial protein has different degrees of heat or shelf stability. (67−69) Moreover, colicins ...

A critical role for bacterial lytic transglycosylases in the clearance of novel, toxic cell wall turnover products that accumulate during vegetative growth is identified through genetic approaches and ...

This work is based on the idea that targeting protein stability or inhibiting proper protein folding in the membrane/periplasmic space might abolish antimicrobial resistances (AMR) in Gram-negative ...

Insect cell mediated recombinant protein expression Insect cells necessitate the use of an intermediate – baculovirus –to enable protein expression. Baculoviruses are a varied group of DNA ...

An international collaborative study led by U.S and Chinese scientists was the first to show that the extracellular autophagy regulator, sequestosome-1 (SQSTM1), mediates septic death in mice by ...