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Blood tests could pave the way for distinguishing between Alzheimer’s, Parkinson’s and some dementias, aiding early treatment for brain diseases.
Proteins are essential to biology, and they have to assume the correct three-dimensional structure in order to work properly... | Cell And Molecular Biology ...
MiROM identifies proteins by using mid-infrared light to detect molecular vibrations – essentially the natural "dance" of molecules within protein structures. Unlike optical spectroscopy, which ...
Researchers from Helmholtz Munich and the Technical University of Munich have developed a novel method to track cancer ...
Alzheimer’s may be driven by more than just plaques—scientists have discovered 200+ hidden proteins that could be quietly harming the brain.
For decades, the story of Alzheimer’s research has been dominated by a battle between amyloid-beta and tau amyloids, both of which can kill neurons and impact the brain’s abil ...
A master of protein origami Johns Hopkins chemist Stephen Fried has spent decades investigating how protein cells fold, unfold, and misfold, a cause of many neurodegenerative diseases and our ...
In this work, the researchers showed how water molecules near a protein surface can influence misfolding. A mutation that is related to tauopathies has a subtle effect on water's dynamic structure in ...
The thinking was that proteins needed to be big in order to carry out complex chemistry. But in fact a lot of the new proteins turning up were smaller than 100 amino acids long.
Tech & Science First synthetic ‘mini prion’ shows how protein misfolding multiplies Scientists plan to explore potential applications, including the development of new diagnostic and ...
Full-length p53 protein expressed on induction of readthrough by these agents is capable of transactivating p53 target genes such as CDKN1A and PUMA and inducing cell death by apoptosis. Thus, ...