Capstan Therapeutics scientists demonstrate that lipid nanoparticles can engineer CAR T cells within the body without laboratory cell manufacturing and ex vivo expansion. The method using targeted ...

Scientists have discovered tumors can tap a nontraditional pathway to acquire lipoproteins—molecules that transport fat in blood—which enriches cancer cells with an antioxidant shield to ...

NewAmsterdam Pharma’s push to show a cholesterol drug can prevent Alzheimer’s disease has passed another test. The phase 3 sub-study tracked significant changes in an Alzheimer’s biomarker ...

Join an expert panel as they explore the dynamic landscape of lipid-based drug delivery systems (DDS) regarding the current research trends and innovation, followed by a deeper look into real-world ...

Phase III trial data support obicetrapib's lipid controlling effects in high-risk individuals without sufficient response to other lipid-lowering therapies. Obicetrapib is a highly selective CETP ...

A schematic illustration of the role of DHHC5 and CRYBG1 in controlling lacteal function and intestinal lipid absorption by maintaining the lipid raft association of VEGFR2.

Bulding a cardiolipin binding site into a computationally designed transmembrane protein uncovers how proteins can recognize specific lipids and use them to regulate their function.

Oregon Health & Science University, in collaboration with Oregon State University, has discovered the structural organization and protein components of a lipid-transfer complex known as LPD-3 ...

CHICAGO — Two novel agents targeting angiopoietin-like protein 3 demonstrated safety and lipid-lowering capabilities in phase 2 trials, according to findings presented at the American ...

Key Enzyme in Lipid Metabolism Linked to Immune System Aging Decreased activity of the enzyme ELOVL2 accelerates white blood cell aging and alters the expression of cancer-associated genes, new ...

We found that nuclear envelope-associated lipid droplets (NE-LDs) were enriched in cholesteryl esters compared to lipid droplets in the cytoplasm. Correlative light-volume-electron microscopy revealed ...

Merck joins a growing list of companies targeting lipoprotein(a), high levels of which are associated with an elevated risk of adverse cardiovascular outcomes.