Researchers demonstrated that systemic factors from young mice can rejuvenate the aging retina by alleviating cellular senescence and restoring function.

In this paper, we demonstrate that two-photon excitation fluorescence lifetime imaging can provide critical morphological information of the retinal pigment epithelium (RPE) cells and facilitate ...

A new study identifies how the molecule, called ApoM, can clear harmful cholesterol deposits linked to macular degeneration as well as certain types of heart ailments.

Elmiron (Regd) (pentosan polysulfate sodium), the only oral medication approved by the United States Food and Drug Administration for this condition, was linked in recent years to serious health ...

While age-related ECM remodeling is linked to outer retinal disease, its fundamental role in mechanical homeostasis remains unclear. In our study, we quantified changes in the mechanical state of ...

Background/aims Tumour necrosis factor-α (TNF-α) is a key mediator of ocular inflammation and its interaction with the retinal pigment epithelium (RPE) may be a driving force in vitreoretinal ...

The following is a summary of “Hyperreflective Foci Along the Retinal Pigment Epithelium Predict the Onset of Large Choroidal Hypertransmission Defects in AMD,” published in the February 2025 issue of ...

Retinitis pigmentosa is a rare visual disorder that affects a layer of tissue in the back of the eye known as the retina—shown here in a colored scanning electron micrograph. The light-detecting ...

Discover a functional monolayer in vitro model of retinal pigment epithelium generated from human iPSCs.

All the latest science news on retinal pigment epithelium from Phys.org. Find the latest news, advancements, and breakthroughs.

ABSTRACT: Purpose: The primary aim of this paper is to design, create, and improve functional and artificial Bruch’s membranes (BM) using bioengineering techniques, which can be applied in the ...