What if mRNA vaccines could be made more powerful and less irritating? Scientists at the University of Pennsylvania have found a way to do just that—by tweaking a key molecule in the vaccine’s ...

Borrowing from the anti-inflammatory properties of olive oil, Penn Engineers used a century-old chemical reaction to redesign ...

As millions of people know firsthand, the most common side effect of mRNA vaccines like the COVID-19 shot is inflammation: ...

As millions of people know firsthand, the most common side effect of mRNA vaccines like the COVID-19 shot is inflammation: ...

An easy method for efficiently identifying proteins that interact with bioactive molecules has been developed by chemical biologists at RIKEN. This innovation, published in ChemBioChem, could help to ...

To build proteins, cells rely on a molecule called transfer RNA, or tRNA. tRNAs act like protein-building couriers, where ...

To build proteins, cells rely on a molecule called transfer RNA, or tRNA. tRNAs act like protein-building couriers, where ...

To build proteins, cells rely on a molecule called transfer RNA, or tRNA. tRNAs act like protein-building couriers, where they read the genetic instructions from messenger RNA, mRNA, and deliver the ...

Screening mRNA delivery and expression The general approach involves designing protein barcodes, which are genetically encoded short amino acid sequences that can be added to protein-coding DNA.

Instead of modifying T cells outside the body, Capstan uses an in vivo messenger RNA (mRNA) approach to provide a set of instructions for cells to make CAR proteins to fight cancer and autoimmune ...