By tethering RNA polymerase with the coupling transcription factor NusG or its paralog or version, RfaH, which threads the ...

Within a cell, DNA carries the genetic code for building proteins. To build proteins, the cell makes a copy of DNA, called mRNA. Then, another molecule called a ribosome reads the mRNA, translating it ...

Within a cell, DNA carries the genetic code for building proteins. To build proteins, the cell makes a copy of DNA, called mRNA. Then, another molecule called a ribosome reads the mRNA ...

He thought the ribosome would read the three-letter codon C[8-oxo-G] ... Simms then deleted the gene for a factor that releases the ribosome from the mRNA when it jams.

These molecules, also called messenger RNA (mRNA) due to the genetic information encoded on them, are read by ribosomes in a stepwise manner. Defined start and stop signals on the mRNA direct this ...

“We wanted to know how quickly a human ribosome can read the genetic code, how quickly it finds the tRNA that’s complementary to the mRNA,” explained said co-first author Mikael Holm, PhD.

Ribosome confronted with a string of these modified bases was seen to ‘slip’ around 10% of the time, causing the mRNA to be misread and unintended proteins to be produced, which was enough to ...

Ribosome researchers have long focused most of their attention on this neat, central area where mRNA is read and amino acids are joined together; they’ve spent less time studying the ribosomes ...