By tethering RNA polymerase with the coupling transcription factor NusG or its paralog or version, RfaH, which threads the ...

Then, another molecule called a ribosome reads the mRNA, translating it into protein. But this step has been a visual mystery: scientists previously did not know how the ribosome attaches to and ...

Within a cell, DNA carries the genetic code for building proteins. To build proteins, the cell makes a copy of DNA, called mRNA. Then, another molecule called a ribosome reads the mRNA, translating it ...

The mRNA specifies, in triplet code, the amino acid sequence of proteins; the code is then read by transfer RNA (tRNA) molecules in a cell structure called the ribosome.

A ribosome is an intercellular structure made of both RNA and protein, and it is the site of protein synthesis in the cell. The ribosome reads the messenger RNA (mRNA) sequence and translates that ...

Similarly, ribosomes without the ribosomal protein RPL10A are less likely to bind to mRNA that codes for another crucial set of embryonic development proteins—ones involved in what’s called ...

Multiple ribosomes work to translate mRNA into protein. Researchers found that these proteins may help each other get out of tight spots on the nucleic acid chain. ©istock, ... Previous studies showed ...

Errors in synthesis or processing may, however, lead to the production of mRNAs that lack termination signals, causing the ribosome to stall while still attached to the mRNA and the growing protein.

An easy method for efficiently identifying proteins that interact with bioactive molecules has been developed by chemical biologists at RIKEN. This innovation, published in ChemBioChem, could help to ...

Protein synthesis: Ribosome recycling as a drug target. Ludwig-Maximilians-Universität München. Journal Nature DOI 10.1038/nature20821 ...