Sarcoplasmic reticulum (SR): A specialised network of membranes in muscle fibres responsible for the storage, release, and reuptake of Ca2+ during contraction and relaxation.

The mechanism of Ca 2+ uptake and release by the sarcoplasmic reticulum during the contraction and relaxation cycle of the fibre became central to muscle biochemistry and was analysed in detail 57.

The lipid-containing membranes of the sarcotubular and reticular system of animal-muscle fragmented sarcoplasmic reticulum (fsr) exhibit both calcium uptake and adenosine triphosphatase (ATPase ...

This new muscle fibre design could result in a muscle that contracts rapidly while retaining strength. The paucity of myofibrils and the high volume occupied by the sarcoplasmic reticulum favour ...

Conversely, fibres low in myofibrils with an abundance of sarcoplasmic reticulum and numerous mitochondria are present in muscles that develop increased speed of contraction.

As food is digested and nutrients are absorbed, there is a lot of movement in the gut. Scientists have now shown that a ...

This calcium activates another ion channel called ryanodine receptor (RyR1 in muscle cells) which releases even more calcium stored inside the sarcoplasmic reticulum to the cytoplasm of the cell.

The rhythmic contraction of smooth muscle cells helps break down food and absorb nutrients. Disruptions to this process lead to a range of gut motility disorders. ... in the sarcoplasmic reticulum.

Skeletal muscle contraction is activated through voltage dependent release of Ca2+ from the intracellular storage location, the sarcoplasmic reticulum (SR) through ryanodine receptors (RyR). Ca2+ ...

Morris T.E. and Sulakhe P.V. (1997) Sarcoplasmic reticulum Ca 2+-pump dysfunction in rat cardiomyocytes briefly exposed to hydroxyl radicals. Free Radic Biol Med 22:37–47.