Transmembrane signaling involves sensing and communicating with the extracellular environment. Part of the transmembrane signaling is a process known as autoproteolysis, which is key in different ...

Extracellular Nucleotide Release and Signaling In their physiologic state, mammalian cells contain high concentrations of ATP (5 to 8 mM).

Recent studies provide new insights into signaling by mutant KRAS, inhibitors of which have provided modest benefits for patients.

This graphic illustrates paracrine adhesion signaling on small extracellular vesicles, which secretes a protein called galectin-3, which promotes endocytosis so the vesicle can be absorbed into ...

Signal transduction was strictly polarized to the serosal side of the epithelium, dependent on the extracellular and sequential hydrolysis of CDNs to adenosine by the ectonucleosidases ENPP1 and CD73, ...

This study reveals that neutrophil extracellular traps (NETs) drive macrophage-derived chemokine production (CXCL9/10/11) to promote CD8+ T cell ...