Not A Relay Race, But A Team Game: New Model For Signal Transduction In Cells. ScienceDaily. Retrieved June 4, 2025 from www.sciencedaily.com / releases / 2007 / 06 / 070627222835.htm.

Gleevec, which hits both p210 BCR-ABL and c-kit, turned out to be one of the first examples of a multi-targeted kinase inhibitor—“therapeutic shrapnel,” in the words of Judith Sebolt-Leopold ...

These results demonstrate that Lyn is an important component of the signal transduction pathway specific to FLT3/ITD and ... c-Kit, and epidermal ... and improve prognosis in a mouse model.