The development of prodrugs — chemically modified versions of pharmacologically active agents that must undergo transformationin vivoto release the active drug — is a well-established strategy ...

To further enhance p -cresol reduction, 4-methylphenyl phosphate synthase CreIH from Corynebacterium glutamicum ATCC 13032 was introduced. By increasing the number of cre IH genes, the recombinant ...

Acetonitrile for HPLC, ammonium acetate, sodium chloride, and anhydrous sodium dihydrogen phosphate were purchased from Th. Geyer Ingredients GmbH & Co. KG (Höxter-Stahle, Germany). Sodium hydroxide ...