Northwestern Medicine scientists have mapped the complete structure of a voltage-gated sodium channel, proteins in the membrane of cells that play an important role in many diseases. The findings ...

Sodium channels are implicated in many serious conditions such as heart disease, epilepsy and pain, making them an important potential target for drug therapies. Unfortunately, there is still much ...

Scientists have determined the atomic structure of a sodium channel, a pore in membranes of excitable cells, such as brain or heart cells, that emit electrical signals. They gate charged particles ...

Voltage-gated sodium (Nav) channels are crucial for action potential initiation in excitable cells. Here the authors present the complete structure of prokaryotic NavMs in a fully open state ...

Sodium channels are potential target for drug therapies as they are implicated in many serious conditions such as heart disease, epilepsy and pain.

Scientists have determined the atomic structure of a sodium channel, a pore in membranes of excitable cells, such as brain or heart cells, that emit electrical signals. They gate charged particles ...

But by rethinking the shape of carbon at the microscopic level, the team found a workaround. The cone and disc structures offer curvature and spacing that welcome sodium and potassium ions without ...

Crystal structures of the microbial rhodopsin KR2, a recently discovered light-driven sodium pump, reveal the translocation pathway of sodium ions and shed light on the molecular mechanism of ion ...

New research provides fresh and unexpected insight into the structure of sodium channels and, specifically, one of its components -- ²-subunit molecules -- which are responsible for 'fine-tuning ...

Estimated sodium intake of more than 3.7 g per day was associated with adverse cardiac remodeling, worse systolic strain and worse diastolic e’ velocity, according to research published in ...

An interview with Professor Artem Oganov about his recent findings - the crystal structure of sodium boride using his USPEX predictor.

Jun 07, 2024 New cathode structure boosts stability and performance of sodium-ion batteries (Nanowerk Spotlight) Lithium-ion batteries, with their high energy density and long lifetimes, have ...