Amino acids play a fundamental role in regulating how cells respond to drugs. These molecules, which form proteins, act like ...

Emerging research positions TUDCA, a bile acid compound, as a promising neuroprotective agent against Alzheimer’s, ...

Researchers from the Max Planck Institute of Immunobiology and Epigenetics in Freiburg and ETH Zurich have created the first integrated map detailing the metabolic and molecular changes in human blood ...

High-resolution cryo-electron microscopy makes it possible to study complex enzymatic processes in detail. With this method, a research team of the University of Potsdam and Humboldt-Universität ...

Tridecanoic acid (C13) is a rare, odd-chain saturated fatty acid produced mainly by gut and rumen microbes, entering metabolic pathways via β-oxidation to support gluconeogenesis and the TCA cycle.

New ways to understand metabolism offer pathways for advances in human health and disease Chinese researchers have decoded the metabolic cycle of yeast using mathematical analysis, revealing striking ...

The tricarboxylic acid cycle (TCA cycle, also known as the citric acid, or Krebs cycle) is considered to be one of these fundamental chemical reaction networks for aerobic organisms (and anaerobic ...

The primary input for the TCA cycle is acetyl coenzyme A, which can be produced from lipid, carbohydrate, and protein catabolism as the result of fatty acid β‐oxidation, pyruvate decarboxylation after ...

Ex vivo experiments have shown that Gln can be a source of carbons for TCA cycle intermediates in the retina and contribute to amino acid biosynthesis (Du, Cleghorn, Contreras, Linton, et al., 2013; ...

multiomics Peg-IFNα chronic hepatitis B HBV HBsAg seroclearance functional cure fatty acid metabolism citrate cycle (TCA cycle) immunity therapy Read this article To access this article, please review ...