They found significant telomere shortening only in classical Werner Syndrome, Berardinelli-Seip Congenital Lipodystrophy type 2, and Dyskeratosis Congenita.

Here we have shown that telomere dysfunction in p53 mutant mice promotes generation of NRTs, accelerates carcinogenesis and shifts the tumour spectrum toward one dominated by carcinomas.

Telomeres and biological age Telomeres are maintained by the enzyme telomerase. This adds to the telomeres, preventing them from shortening as rapidly, thereby allowing the cells to live for longer.

Epigenetic modifications are key players in the regulation of fly and yeast telomeres, and recent studies indicate that the same applies in mammalian cells. These findings have implications for ...

This supports the hypothesis that telomere shortening is an early event in human tumor development, and that such shortening could contribute to the chromosome mutagenesis and instability that are ...

Shorter leukocyte telomere length linked to higher incidence rates of stroke, dementia, late-life depression as composite and individually.

Experts break down new research that says vitamin D may prolong life by slowing the shortening of telomeres, protective caps on chromosomes that wear with age.

Experts break down new research that says vitamin D may prolong life by slowing the shortening of telomeres, protective caps on chromosomes that wear with age.

Since the mode of action of potential telomerase inhibitors would require that telomeres shorten before inhibition of cell proliferation is initiated, there may be a significant delay in efficacy.

The Kansas Department of Wildlife and Parks is again shortening the trout season amid rising costs. Fishing changes frustrated state lawmakers.

Adults who reported weekly nightmares were more than three times as likely to die before the age of 70.

In conclusion, cyanobacterial harmful algal blooms are more than an environmental nuisance—they may be a key factor in shortening the lives of individuals with amyotrophic lateral sclerosis.