Third-generation (gen-3), single-molecule sequencing technology is not only about making quantifiable enhancements to second-generation (gen-2) capabilities, but also about improving data quality ...

Third Generation Sequencing, also known as long-read sequencing, represents a breakthrough in the realm of genomics. Unlike the previous methods which required DNA fragmentation, TGS reads long ...

Home News NHGRI Fortifies Third-Generation Sequencing Development with $18M September 16, 2010 Boston University and Scripps, studying single-molecule nanopore techniques, received the largest grants.

Third-generation sequencing methods promise longer sequence reads without the challenges of genome assembly. Beyond simple DNA sequencing, these technologies can reveal epigenetics, transcriptomics, ...

Next-generation sequencing (NGS) provides researchers from various scientific fields the ability to cast a wide net and explore complex pathways and biological processes. With NGS, scientists can take ...

While third generation sequencing comes with many notable advantages, it also faces several prominent disadvantages. Among these is the relatively low accuracy: despite improvements driven by ...

It is best for small whole-genome sequencing, targeted gene sequencing, metagenomics, and CRISPR validation. The NextSeq 550 has been in use since 2018 and is great for mid-range projects such as ...

Next generation sequencing technologies allow clinicians and scientists to determine the precise order of nucleotides – or building blocks -- in a DNA sequence. “This special issue of the journal ...