People living in high pollution areas may rack up DNA glitches that trigger lung cancer, scientists suggest July 2 in Nature. Those glitches can include mutations that hobble the very genes that ...

Researchers have discovered an unusual case where two well-known cancer-related mutations-APC and KRAS-coexisted in a woman with familial adenomatous polyposis (FAP) and a history of endometrial ...

A major breakthrough in cancer genetics has been achieved, paving the way for more effective prevention, early detection, and ...

A newly discovered genetic mutation unique to humans may help explain why we are significantly more vulnerable to cancer than ...

Tumor mutation burden (TMB) is a measurement of the number of mutations carried by tumor cells and an emerging area of focus in biomarker research.

A group led by the Department of Neurosurgery at the Brain Research Institute, Niigata University, has successfully treated a ...

Cancer mutations occur decades before diagnosis Date: February 6, 2020 Source: European Molecular Biology Laboratory Summary: A large-scale pan-cancer analysis of the evolutionary history of ...

High tumor mutation burden predicts immunotherapy response in some, but not all, cancers Further research is needed to identify predictive biomarkers for certain cancers, results suggest ...

Cancer experts have tried, sometimes unsuccessfully, to use the total number of mutations in a tumor, called the tumor mutation burden (TMB), to predict a patient's response to immunotherapy.

In search of a way to reverse the tumors’ radiotherapy resistance, the team tested two compounds, KU-60019 or AZD7762, that inhibit DNA repair on mice bearing tumors with this set of mutations.

Joe Biden: 50% of cancers can be eliminated 01:23. Whoa: That doesn’t mean most cases of cancer are due solely to “bad luck.” It takes multiple mutations to turn cells into tumors — and a ...