Microbiomes in older mice pumped out damaging metabolites that drove endothelial cell senescence, offering potential targets ...

Defective endothelial and platelet NO synthesis represents a major feature of endothelial dysfunction in cardiovascular disease (CVD). To verify whether their circulating “offspring” also show similar ...

This study shows that oral—but not intravenous—lysozyme reshapes gut microbiota to reactivate PI3K–Akt signaling and reverse vascular aging in mice, ...