These proteins can have too many conformations for researchers to keep track of, says Kejia Wu, a postdoctoral researcher ...

By looking for missteps in the intricate process of folding proteins, a project at Purdue University is paving the way for a new generation of therapeutics that strike at the root of these diseases. .

There are around 20,000 proteins in the human proteome, yet only around 100 have had their folding mechanisms studied in detail. This development has the potential to shed light on a number of ...

To better understand the protein folding process that takes place within a cell, Barry Willardson, BYU professor of biochemistry, and Peter Shen, professor of biochemistry at the University of Utah ...

For Fried, an assistant professor of chemistry who has devoted his career to dissecting the intricacies of protein folding, the November 2020 news was both exciting and somewhat disheartening. "I was ...

A comprehensive analysis of over 500,000 human protein variants reveals that 60% of disease-causing missense mutations reduce protein stability In a recent study published in Nature, researchers ...

Each protein has a unique sequence of amino acids—there are 20 common types in the human body—that determines how it folds into its proper three-dimensional structure.

Scientists at UCL have discovered a novel role played by ribosomes during the folding of new proteins in cells, described in their paper in Nature. Ribosomes, the cell's dedicated molecular ...