Borrowing from the anti-inflammatory properties of olive oil, Penn Engineers used a century-old chemical reaction to redesign ...

As millions of people know firsthand, the most common side effect of mRNA vaccines like the COVID-19 shot is inflammation: ...

To build proteins, cells rely on a molecule called transfer RNA, or tRNA. tRNAs act like protein-building couriers, where they read the ...

Screening mRNA delivery and expression The general approach involves designing protein barcodes, which are genetically encoded short amino acid sequences that can be added to protein-coding DNA.

Ribosomes are tiny molecular machines inside all living cells that build proteins, and ribosome biogenesis is the complex, multi-step process by which they are made. During brain development ...

Instead of modifying T cells outside the body, Capstan uses an in vivo messenger RNA (mRNA) approach to provide a set of instructions for cells to make CAR proteins to fight cancer and autoimmune ...

RNA post-transcriptional modifications are ubiquitous across all organisms and serve as fundamental regulators of cellular homeostasis, growth, and stress adaptation. Techniques for the simultaneous ...