A Protein-Sensing Molecular Switch Alters Facial Features The mTORC1 signaling pathway senses nutritional information and influences craniofacial development in mice.

This work is published in Nature Aging in the paper, “ A mild increase in nutrient signaling to mTORC1 in mice leads to parenchymal damage, myeloid inflammation, and shortened lifespan.

Role of mTOR signaling in cytotoxic T-cell differentiation The activity of mTOR complexes, mTORC1, and mTORC2, differentially dictates cytotoxic T lymphocyte fate and memory T lymphocyte formation.