Background Genome-wide association studies have identified an exon 6 CTRB2 deletion variant proposed to increase pancreatic cancer risk. Conclusions This mouse strain provides evidence that the exon 6 ...
15 Department of Gastroenterology and Hepatology, Singapore General Hospital, Singapore Background Metabolic dysfunction-associated steatotic liver disease (MASLD) affects over 30% of the general ...
Objective The significance of the liver-microbiome axis has been increasingly recognised as a major modulator of autoimmunity. The aim of this study was to take advantage of a large well-defined ...
Objective In the tumour microenvironment, critical drivers of immune escape include the oncogenic activity of the tumour cell-intrinsic osteopontin (OPN), the expression of programmed death ligand 1 ...
Background Gastric intestinal metaplasia (IM) is a precancerous stage spanning a morphological spectrum that is poorly represented by human cell line models. Objective We aim to establish and ...
Objective To determine whether new users of proton pump inhibitors (PPIs) are at an increased risk of gastric cancer compared with new users of histamine-2 receptor antagonists (H2RAs). Design Using ...
2 Institute of Digestive Disease and the Department of Medicine and Therapeutics, State Key Laboratory of Digestive Disease, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong ...
Dr S Blum, Department of Immunology, Nestlé Research Centre, Vers-Chez-les-Blanc, Ch-1000 Lausanne 26, Switzerland. Email: stephanie.blum-sperisen{at}rdls.nestle.com BACKGROUND AND AIM Intestinal ...
Correspondence to Professor Xiao Xu, Department of Hepatobiliary and Pancreatic Surgery, the First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310003, China; ...
We read with great interest the recent article by Turner et al published in Gut , which evaluated the use of faecal calprotectin to define preclinical stages of Crohn’s disease (CD) in asymptomatic ...
Objective Faecal microbiota transplantation (FMT) has variable efficacy in treating UC. Recently, oral lyophilised FMT was found to induce remission in patients with UC, with one donor having 100% ...
2 Henan Key Laboratory of Cerebrovascular Diseases, The First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, China ...
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