A Real-Time PCR assay for telomere length involves determining the Telomere-to-Single Copy Gene (T/S) ratio, which is demonstrated to be proportional to the average telomere length in a cell.

Aug 4, 2025 · The telomere’s role in aging becomes clear when you realize they’re not endlessly replenished. In most somatic (body) cells, telomeres shorten with every division, slowly ticking down …

2 days ago · The telomere itself is a long stretch of a specific short DNA sequence repeated over and over hundreds of times. At the very end of the telomere is a sort of knot not called the "T-loop," which …

Mar 8, 2019 · We’ll dive into the recent research surrounding telomere shortening, cancer, and aging. You’ll learn how diet, exercise, and stress management affect telomeres.

While telomere shortening has been linked to the aging process, it is not yet known whether shorter telomeres are just a sign of aging like gray hair or actually contribute to aging.

Mar 30, 2025 · Telomere length varies between individual chromosomes, they do not have the same telomere length in all individuals. This can affect the measurement of telomeres.

Several single nucleotide polymorphisms at different loci, identified through genome-wide association studies, influence inter-individual variation in telomere length. In addition to genetic factors, …

Nov 20, 2025 · telomere, segment of DNA occurring at the ends of chromosomes in eukaryotic cells (cells containing a clearly defined nucleus). Telomeres are made up of repeated segments of DNA …

Jul 31, 2025 · During cell division, the DNA replication machinery cannot fully copy the very end of a chromosome, leading to a slight shortening of the telomere with each round of division.

Feb 20, 2023 · Each time a cell divides, some part of the repeating sequence in a telomere is lost. When telomeres become too short to function effectively, a cell either dies or stops dividing.